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CN Bio appoints Joseph Parisi as US Director of Sales to support accelerated growth in key OOC market

CN Bio, a leading Organ-on-a-Chip (OOC) company that designs and manufactures single- and multi-organ microphysiological systems (MPS), today announced the appointment of Joseph Parisi as US Director of Sales. In his new role, Joe will lead the expansion of the Company’s sales and support activities for the US market to address the growing demand for new alternative methodologies (NAMs) in preclinical drug discovery.
news-medical.net/news/20240131/CN-Bio-appoints-Joseph-Parisi-as-US-Director-of-Sales-to-support-accelerated-growth-in-key-OOC-market.aspx

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Gene therapy could prolong survival in some people with arrhythmogenic right ventricular cardiomyopathy

A new study in mice shows that replacement of a dysfunctional gene could prolong survival in some people with arrhythmogenic right ventricular cardiomyopathy (ARVC), a rare inherited disorder in which the muscular walls of the heart progressively weaken and put patients at risk of dangerous irregular heartbeats.
news-medical.net/news/20240130/Gene-therapy-could-prolong-survival-in-some-people-with-arrhythmogenic-right-ventricular-cardiomyopathy.aspx

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MGI Unveils Comprehensive Expansion of Automation Product Lines for Life Science and Healthcare Research

MGI Tech Co., Ltd. (referred to as MGI), a leading provider of cutting-edge tools and technology for life science and healthcare research, today announced a strategic expansion of its automation product lines.
news-medical.net/news/20240130/MGI-Unveils-Comprehensive-Expansion-of-Automation-Product-Lines-for-Life-Science-and-Healthcare-Research.aspx

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Common biomarker test could be misguiding treatment for some Black women with breast cancer

A common test used to decide whether breast cancer patients should get chemotherapy may be making bad recommendations for some Black women, leading them to forgo chemotherapy when it might have helped, according to new research from the University of Illinois Chicago.
news-medical.net/news/20240129/Common-biomarker-test-could-be-misguiding-treatment-for-some-Black-women-with-breast-cancer.aspx

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Dr. Chao Ma: Pioneering 'Leukemia-on-a-Chip' for CAR T Cell Therapy at SLAS 2024

NewsMedical speaks with Chao Ma, Ph.D. a Research Assistant Professor at New York University Tandon School of Engineering, ahead of his presentation at SLAS 2024.
news-medical.net/news/20240129/Dr-Chao-Ma-Pioneering-Leukemia-on-a-Chip-for-CAR-T-Cell-Therapy-at-SLAS-2024.aspx

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Europe gears up for future pandemics with AI-powered "PAIR" project

The new EU-funded five-year project PAIR just kicked off in Copenaghen with the participation of 20 partners from 7 countries.
news-medical.net/news/20240127/Europe-gears-up-for-future-pandemics-with-AI-powered-PAIR-project.aspx

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Sclerostin may protect against heart disease in patients with type 2 diabetes

A study carried out by the MP20-Biomarkers of Metabolic and Bone Diseases research group at the Biohealth Research Institute in Granada (ibs.GRANADA), led by UGR Professor Manuel Muñoz Torres, has provided significant insights into the role of sclerostin in protecting against atherosclerosis in patients with type 2 diabetes.
news-medical.net/news/20240126/Sclerostin-may-protect-against-heart-disease-in-patients-with-type-2-diabetes.aspx

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Study establishes the ideal immunosuppression regimen for pig-to-human kidney xenotransplantation

Currently used Food and Drug Administration-approved transplant drugs -; with the addition of an also already FDA-approved complement inhibitor -; are the optimal immunosuppression regimen for pig-to-human kidney transplants, according to a landmark discovery by University of Alabama at Birmingham investigators.
news-medical.net/news/20240125/Study-establishes-the-ideal-immunosuppression-regimen-for-pig-to-human-kidney-xenotransplantation.aspx

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Cleveland Clinic and IBM researchers reveal strategy for identifying new immunotherapy targets through AI

Researchers from Cleveland Clinic and IBM have published a strategy for identifying new targets for immunotherapy through artificial intelligence (AI).
news-medical.net/news/20240123/Cleveland-Clinic-and-IBM-researchers-reveal-strategy-for-identifying-new-immunotherapy-targets-through-AI.aspx

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Novel software measures the significance of specific genomic biomarkers to help predict diseases

IntelliGenes, a first of its kind software created at Rutgers Health, combines artificial intelligence (AI) and machine-learning approaches to measure the significance of specific genomic biomarkers to help predict diseases in individuals, according to its developers.
news-medical.net/news/20240123/Novel-software-measures-the-significance-of-specific-genomic-biomarkers-to-help-predict-diseases.aspx

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Body mass index found to mediate causal associations between Helicobacter pylori infections and coronary artery disease risk

Coronary heart disease (CHD) and H. Pylori.
news-medical.net/news/20240123/Body-mass-index-found-to-mediate-causal-associations-between-Helicobacter-pylori-infections-and-coronary-artery-disease-risk.aspx

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Innovative COVID-19 test prototype uses bioluminescence for speedier results

Researchers used a luciferase-independent luminescence test to investigate whether the wild-type SARS-CoV-2 spike protein possesses pseudo-luciferase activity for Cypridina luciferin.
news-medical.net/news/20240122/Innovative-COVID-19-test-prototype-uses-bioluminescence-for-speedier-results.aspx

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AI scores breakthrough in anemia treatment with novel PHD inhibitor

Clinical stage generative artificial intelligence (AI)-driven biotechnology company InSilico Medicine ("InSilico"), today announced that the Journal of Medicinal Chemistry, an ACS Publications journal focusing on critical studies about molecular structure and biological activity, has published the company's discovery of a novel PHD inhibitor for the treatment of anemia.
news-medical.net/news/20240119/AI-scores-breakthrough-in-anemia-treatment-with-novel-PHD-inhibitor.aspx

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Unveiling the cellular mechanisms of engram consolidation and memory refinement

Think of a time when you had two different but similar experiences in a short period. Maybe you attended two holiday parties in the same week or gave two presentations at work.
news-medical.net/news/20240119/Unveiling-the-cellular-mechanisms-of-engram-consolidation-and-memory-refinement.aspx

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TRPC3 emerges as key player in preventing damage from alcohol-associated liver disease

Excessive alcohol intake is strongly associated with alcohol-associated liver disease (ALD) which accounts for 25% and 30% of deaths from cirrhosis and hepatocellular carcinoma. Impairment of Ca2+ influx and Ca2+-mediated signaling in ALD suggests that Ca2+ channels are important in ALD pathological progression.
news-medical.net/news/20240116/TRPC3-emerges-as-key-player-in-preventing-damage-from-alcohol-associated-liver-disease.aspx

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XRCC1 shows potential as a prognostic and immunological pan-cancer biomarker

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 1, entitled, "XRCC1: a potential prognostic and immunological biomarker in LGG based on systematic pan-cancer analysis."
news-medical.net/news/20240130/XRCC1-shows-potential-as-a-prognostic-and-immunological-pan-cancer-biomarker.aspx

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Equity through virtual visits: Telehealth revolutionizes hypertension care for Medicaid recipients

A new study in the peer-reviewed journal Telemedicine and e-Health found that hypertension management via telehealth increased among Medicaid recipients regardless of race and ethnicity during the COVID-19 pandemic.
news-medical.net/news/20240130/Equity-through-virtual-visits-Telehealth-revolutionizes-hypertension-care-for-Medicaid-recipients.aspx

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Machine learning unlocks personalized approach to early ovarian cancer detection

For over three decades, a highly accurate early diagnostic test for ovarian cancer has eluded physicians.
news-medical.net/news/20240129/Machine-learning-unlocks-personalized-approach-to-early-ovarian-cancer-detection.aspx

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European scientists target high-risk childhood cancer with liquid biopsy

Neuroblastoma mainly affects toddlers and young children - in the EU region there are 1500 new cases per year.
news-medical.net/news/20240129/European-scientists-target-high-risk-childhood-cancer-with-liquid-biopsy.aspx

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Gene activity plays key role in immune cell production, study shows

As people age or become ill, their immune systems can become exhausted and less capable of fighting off viruses such as the flu or COVID-19.
news-medical.net/news/20240127/Gene-activity-plays-key-role-in-immune-cell-production-study-shows.aspx

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Sclerostin may protect against heart disease in patients with type 2 diabetes

A study carried out by the MP20-Biomarkers of Metabolic and Bone Diseases research group at the Biohealth Research Institute in Granada (ibs.GRANADA), led by UGR Professor Manuel Muñoz Torres, has provided significant insights into the role of sclerostin in protecting against atherosclerosis in patients with type 2 diabetes.
news-medical.net/news/20240126/Sclerostin-may-protect-against-heart-disease-in-patients-with-type-2-diabetes.aspx

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Study links European West Nile outbreaks to agriculture, urbanization, and bird migration

The spread of West Nile virus in Europe is strongly linked to agricultural activities, urbanization, and bird migration, according to a modelling study published January 25, 2024 in the open-access journal PLOS Pathogens by Lu Lu from the University of Edinburgh, UK, and collaborators belonging to a large European collaborative consortium under the VEO (Versatile Emerging infectious disease Observatory) project.
news-medical.net/news/20240125/Study-links-European-West-Nile-outbreaks-to-agriculture-urbanization-and-bird-migration.aspx

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Ancient Brazilian genomes may hold the secrets of treponemal evolutionary history

Study reconstructs four ancient treponeme genomes from 2,000-year-old Brazilian remains, revealing their close relation to the bejel-causing Treponema pallidum endemicum and challenging previous hypotheses about treponeme subspecies adaptability.
news-medical.net/news/20240125/Ancient-Brazilian-genomes-may-hold-the-secrets-of-treponemal-evolutionary-history.aspx

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RNA Therapies in Liver Disease: Insights from Ochre Bio's CEO

In this interview, we speak with Jack O'Meara, co-founder and CEO of Ochre Bio, a pioneering force in liver disease treatment. O'Meara shares insights into Ochre Bio's innovative RNA therapies, their approach to tackling liver disease, and the company's vision for the future.
news-medical.net/news/20240124/RNA-Therapies-in-Liver-Disease-Insights-from-Ochre-Bios-CEO.aspx

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C-Path's TRxA launches 2024 grants to boost next-gen therapeutics

Critical Path Institute's (C-Path) Translational Therapeutics Accelerator (TRxA) today announced its 2024 global Request for Proposals for its Breakthrough Research and Innovation in Drug Development Grants, also known as BRIDGe.
news-medical.net/news/20240123/C-Paths-TRxA-launches-2024-grants-to-boost-next-gen-therapeutics.aspx

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Microgravity may make space veggies more prone to bacteria

Lettuce and other leafy green vegetables are part of a healthy, balanced diet -; even for astronauts on a mission.
news-medical.net/news/20240122/Microgravity-may-make-space-veggies-more-prone-to-bacteria.aspx

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New research center seeks to harness the positive powers of fungi

A new research center focused on harnessing the positive powers of fungi is being established at Cranfield University with a £7.2 million injection of funding from Research England.
news-medical.net/news/20240119/New-research-center-seeks-to-harness-the-positive-powers-of-fungi.aspx

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Insilico Medicine leverages AI to identify promising new target for breast and gynecological cancers

Insilico Medicine("Insilico"), a clinical stage generative artificial intelligence (AI)-driven drug discovery company, recently published an early research that it has identified MYT1 as a promising new therapeutic target for breast and gynecological cancer, and discovered a series of novel, potent, and highly selective inhibitors specifically targeting MYT1.
news-medical.net/news/20240119/Insilico-Medicine-leverages-AI-to-identify-promising-new-target-for-breast-and-gynecological-cancers.aspx

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$2.8M grant targets copper's role in deadly kidney cancer

Copper is an essential trace element required to produce energy in the body and allows humans to live in our atmosphere.
news-medical.net/news/20240117/2428M-grant-targets-coppers-role-in-deadly-kidney-cancer.aspx

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StemSight and ERS Genomics focus on collaboration

License agreement provides StemSight access to CRISPR/Cas9 technology to be applied in development of cell therapies for corneal blindness.
news-medical.net/news/20240117/StemSight-and-ERS-Genomics-focus-on-collaboration.aspx

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